Dean: You guys don't walk enough. You're gonna get flabby. You know, I'm starting to think Junkless has a better sense of humor than you do.
Castiel: Uriel's the funniest angel in the garrison. Ask anyone.
Dean: Cas, hold up. What were you going to tell me?
Castiel: I learned my lesson while I was away, Dean. I serve Heaven, I don't serve man. And I certainly don't serve you.
Dean: Destiny? Don't give me that "holy" crap. Destiny, God's plan... It's all a bunch of lies, you poor, stupid son of a b*tch! It's just a way for your bosses to keep me and keep you in line! You know what's real? People, families - that's real. And you're gonna watch them all burn?
Castiel: What is worth saving?! I see nothing but pain here. I see inside you. I see your guilt, your anger, confusion... In Paradise all is forgiven. You'll be at peace. Even with Sam.
Castiel: I dragged you out of hell, I can throw you back in.
Dean: (On Castiel trying to find God) Try New Mexico, I hear he's on a tortilla.
Castiel: No, he's not on any flatbread.
Raphael: I will find you!
Castiel: Maybe so, but today you're my little b*tch.
Dean: What He Said
Dean: (on phone) Cas, it's Dean. Yeah, room 31 C, basement level, St. James Medical Center -
Castiel: (appears in front of him) I'm there now.
Dean: Yeah, I get that.
Castiel: I'm gonna hang up now.
Castiel: I found a liquor store.
Castiel: I drank it
Castiel: Hey, Ass-butt! (Throws bottle of flaming Holy Water at Michael, burning him up)
Castiel: He'll be back, and angry, but you got your five minutes
Lucifer: Castiel, Did you just Molotov my brother... with Holy Fire?
Castiel: Uh... no?
Lucifer: No one dicks with Michael but me.
(Lucifer snaps his fingers and Castiel explodes)