The series borrows many characters, or at least their names, from the 1997 television series La Femme Nikita. Maggie Q portrays Nikita, the protagonist and a former spy and assassin who has gone rogue and now plans to bring down Division. Q also performs her own stunts. Shane West plays Michael, a Division operative who trained Nikita. He sees Division and its recruits as a kind of family to him, the complete opposite of Amanda, portrayed by Melinda Clarke, Division's psychologist, interrogator, and a master manipulator. Seymour Birkhoff, Division's computer genius and head technician, is portrayed by Aaron Stanford. The head of Division is Percy, played by Xander Berkeley.
In the season one finale, the audience is introduced to a Senator Madeline Pierce, played by Alberta Watson, who also played the part of Madeline in the former La Femme Nikita series (Madeline was that series' counterpart to Amanda). Lyndsy Fonseca portrays Alexandra "Alex" Udinov, a former sex slave and drug addict who was arrested after a robbery and later became Division's newest recruit. She is also a mole that Nikita is using to destroy Division from the inside. Other recruits include Jaden...