Some of my very favourite..if you have any more to add just leave a comment!
The name is Salvatore. As in savior
I'm the most dangerous thing you're ever likely to encounter in your life.
(harassing Stefan about Elena)
I only did it because I wanted to be close to you. Brothers should be close.
(making a pact)
Stefan: I agree.
Damon: And I agree. In fact, we all seem to be in a frenzy of pure agreement.
(on Fell's Church)
Kingdoms rise and kingdoms fall. When you’ve seen enough of them as I have you develop an indifference. And this miserable place is hardly a dot on the map, anyway.
(on the subject of joining Katherine)
Katherine: I didn't mean to hurt you... I'm sorry.
Damon: Katherine?
Katherine: Yes?
Damon: Katherine...
Katherine: Yes, Damon?
Damon: Go to hell.
I can waken things inside you that have been sleeping all your life.
Elena: Where's Stefan?
Damon: Stefan who?
Elena: I'd rather cut my throat.
Damon: An intriguing thought. But I can do it so much more enjoyably.
(to Elena)
Damon: Do you know... that a mole on the neck means you'll be wealthy? Do you mind if I check?
Stefan: I mind.
Damon: But do you matter?
(with Bonnie & 2 werewolves)
Three may be a crowd, but four is enough for a round of bridge, yes?
(to Bonnie whose has a ruler on the werewolves)
You did some very nice work with that but you don’t need it anymore.
They’re in puppy heaven now. Well, puppy hell, more likely, but you don’t need to worry about them, is the point.
(to Bonnie about drinking her blood)
“Never. I’d never take advantage of a sleeping maiden.”
(seeing Elena and Stefan's reunion)
Damon: Very touching. Do you want me to imitate a violin?
(to Bonnie about the bodies in the library)
Now remember to be surprised when they find three dead people at the library—especially the poor bloke they turned into a pile of bones.
(denying the attack of Vickie Bennett)
Elena: The cemetery, remember? The ruined church? The girl you left wandering around there in her slip?
Damon: Sorry, no. And I usually do remember girls I leave wandering in their slips.
(to Bonnie about the dangers about to come in 'Blood Will Tell')
What you’re challenging isn’t beatable. That’s the truth, maybe not in words of one syllable but as simply as I can put it without resorting to sock-puppets.
Stefan: What are you going to do when they come after you?... Kill them all?...
Damon: Why not?
Stefan: Do you want to get caught, Damon?
Damon: I am never caught, little brother.
(to Bonnie about not drinking her blood immediately)
Don’t burst a blood vessel trying to make me too mad. After all, some day you will be ripe. And I’ve got a good memory.
(to Elena)
I told Stefan from the beginning that he was selfish not to share you. Brothers should share things, you know.
(throwing a tree out of a forest in a wild display of power)
I didn't like it there anyway.
Giuseppe: What do you mean, you're not going back(to university)?
Damon: I would have thought even you could understand such a simple sentence, father. Shall I repeat it in Latin for you?
Giuseppe: You are telling me that I... will have to face my friends knowing my son is a... an idler?
Damon:Apparently. If you can call those who fawn on you in the hopes that you will lend them money your friends.
The name is Salvatore. As in savior
I'm the most dangerous thing you're ever likely to encounter in your life.
(harassing Stefan about Elena)
I only did it because I wanted to be close to you. Brothers should be close.
(making a pact)
Stefan: I agree.
Damon: And I agree. In fact, we all seem to be in a frenzy of pure agreement.
(on Fell's Church)
Kingdoms rise and kingdoms fall. When you’ve seen enough of them as I have you develop an indifference. And this miserable place is hardly a dot on the map, anyway.
(on the subject of joining Katherine)
Katherine: I didn't mean to hurt you... I'm sorry.
Damon: Katherine?
Katherine: Yes?
Damon: Katherine...
Katherine: Yes, Damon?
Damon: Go to hell.
I can waken things inside you that have been sleeping all your life.
Elena: Where's Stefan?
Damon: Stefan who?
Elena: I'd rather cut my throat.
Damon: An intriguing thought. But I can do it so much more enjoyably.
(to Elena)
Damon: Do you know... that a mole on the neck means you'll be wealthy? Do you mind if I check?
Stefan: I mind.
Damon: But do you matter?
(with Bonnie & 2 werewolves)
Three may be a crowd, but four is enough for a round of bridge, yes?
(to Bonnie whose has a ruler on the werewolves)
You did some very nice work with that but you don’t need it anymore.
They’re in puppy heaven now. Well, puppy hell, more likely, but you don’t need to worry about them, is the point.
(to Bonnie about drinking her blood)
“Never. I’d never take advantage of a sleeping maiden.”
(seeing Elena and Stefan's reunion)
Damon: Very touching. Do you want me to imitate a violin?
(to Bonnie about the bodies in the library)
Now remember to be surprised when they find three dead people at the library—especially the poor bloke they turned into a pile of bones.
(denying the attack of Vickie Bennett)
Elena: The cemetery, remember? The ruined church? The girl you left wandering around there in her slip?
Damon: Sorry, no. And I usually do remember girls I leave wandering in their slips.
(to Bonnie about the dangers about to come in 'Blood Will Tell')
What you’re challenging isn’t beatable. That’s the truth, maybe not in words of one syllable but as simply as I can put it without resorting to sock-puppets.
Stefan: What are you going to do when they come after you?... Kill them all?...
Damon: Why not?
Stefan: Do you want to get caught, Damon?
Damon: I am never caught, little brother.
(to Bonnie about not drinking her blood immediately)
Don’t burst a blood vessel trying to make me too mad. After all, some day you will be ripe. And I’ve got a good memory.
(to Elena)
I told Stefan from the beginning that he was selfish not to share you. Brothers should share things, you know.
(throwing a tree out of a forest in a wild display of power)
I didn't like it there anyway.
Giuseppe: What do you mean, you're not going back(to university)?
Damon: I would have thought even you could understand such a simple sentence, father. Shall I repeat it in Latin for you?
Giuseppe: You are telling me that I... will have to face my friends knowing my son is a... an idler?
Damon:Apparently. If you can call those who fawn on you in the hopes that you will lend them money your friends.