Emilie annoys me the most since she doesn't even exist, and yet you keep mentioning her...

Amanda? That baby voice got on my nerves, so YES she annoyed me a lot.
Lexi was barely there, so I didn't mind her. Rachel was rather pointless IMO, her storyline could've been much better instead of just making her another short-lived guest star who just POOF disappeared after we found out how "evil" she was.

I love Georgie, but I wouldn't want her as Dan's girlfriend if that's what we're talking about (I did before season 3, but I was disappointed after their hook-up).
Serena... err, she annoys me from time to time, but most of the time I like her, plus she's one of the main characters so it would be sad if she was the most annoying out of these, haha.

Actually, I have a question for you: Who on earth is Emilie?! Can you puh-lease tell us?

Rachel and Georgina!

Yeah, I have the same question - who the hell is Emilie?

But I don't like Rachel the most! With her sad and desperate faces - blah!

I hate both Georgina and Rachel and there's no one called Emilie he used to go out with.

Serena

I really wish i could like Serena...I love her in the books. But Oh. My. God. Open your mouth wider when you talk! She mumbles her way through all her lines argh. And te first season she annoyed me because she doesnt talk about anything and thats why her and dan can't work. Besides the whole parents in love thing lol

I can't even start to like Serena, I liked Blake Lively before, but when I started watching gossip girl. I hated her, I don't really know what it is, I guess I find her slightly annoying, and whorish.
And her laugh gets on my nerves.

This is off topic, but I like Vanessa for him.
But I don't really care for her outside of that relationship