Orochimaru is a missing-nin from Konohagakure. After he defects from Konoha he joins Akatsuki and is paired with Sasori. Once Itachi Uchiha does the same, Orochimaru attempts to use one of his abilities to forcefully take control of Itachi's body. Itachi repels his effort and severs his hand as punishment, forcing Orochimaru to flee the organization in defeat. Upon leaving he takes his severed hand and the ring he wore on it with him. Because of this, as well as the fact that he had intimate knowledge of Akatsuki's secrets and plans, the members of Akatsuki began making every effort possible to find and eliminate him.