Cameron Diaz as Jules Baxter, a contestant on a celebrity dance show and a host to a weight-loss fitness show, who becomes pregnant with her dance partner's baby girl named Emerson
Jennifer Lopez as Holly Castillo, a woman who adopts a baby boy named Kaleb from abroad with her unwilling husband after difficulty conceiving
Elizabeth Banks as Wendy Cooper, Gary's wife and Theo's mother who becomes pregnant after trying for 2 years. Runs the Breast Choice Boutique.
Chace Crawford as Marco, who reunites with an old flame (Rosie) after a turf war between their respective food trucks
Brooklyn Decker as Skyler Cooper, the wife of a much older man named Ramsey, stepmother of Gary who becomes pregnant with twins Aida & Nida
Ben Falcone as Gary Cooper, Wendy's husband, Theo's father, Ramsey's son, Skyler's stepson, and Aida & Nida's older paternal half-brother
Anna Kendrick as Rosie Brennan, who reunites with an old flame (Marco) and fellow food-truck owner and becomes pregnant unexpectedly and has a miscarriage
Matthew Morrison as Evan Webber, who teams with Jules on a celebrity dance show and the father of her baby girl named Emerson
Dennis Quaid as Ramsey Cooper, Skyler's husband, Gary, Aida & Nida's father and Theo's paternal grandfather
Chris Rock as Vic Mac, founder of the "dude group" and father of four.
Rodrigo Santoro as Alex Castillo, Holly's husband who's in the music business and is not ready to have an adopted son named Kaleb
Joe Manganiello as Davis
Rob Huebel as Gabe, a new parent who adjusts to "fatherdom" by bonding with other dads in a city park-based group that is part playgroup, part secret society for dads only
Thomas Lennon as Craig, a father who joins Vic's "dude group"
Amir Talai as Patel, a father who joins Vic's "dude group"
Rebel Wilson as Janice, an eccentric employee at The Breast Choice boutique
Wendi McLendon-Covey as Kara, Holly's co-worker and friend
Dwyane Wade has a cameo as himself
Whitney Port has a cameo as herself
Megan Mullally has a cameo as herself
Taboo has a cameo as himself
Whitney Bischoff has a cameo as herself
Katherine Heigl has a cameo as herself
Serena Williams has a cameo as herself
Kim Fields as Renee Thompson, social worker who helps out a couple with an adoption
Jesse Burch as Hutch Davidson
Josh Segarra as Brett, Rosie's nerd roommate
Mimi Gianopulos as Molly, Rosie's funny roommate who comforts and supports her
Genesis Rodriguez as Courtney, Rosie's roommate
Sean Holland as Joey, Rosie's social worker
Hannah Kahlsulka as Grenda, Skyler's goofy friend at restaurant
Louisa Lytton as Meredith, Skyler's goofy friend
Roxane Hayward as Mickie, Skyler's goofy friend at restaurant
Odette Yustman as Bella, Skyler's goofy friend at restaurant
Dominique McElligott as Sterling, Skyler's goofy friend at restaurant
Joanie Sprague plays a clown at a restaurant
Olivia Scriven, Julia Barnett Tracy, Devin Kelley, Emmanuelle Chirqui, and Karrie Otis play restaurant chefs
Jennifer Lopez as Holly Castillo, a woman who adopts a baby boy named Kaleb from abroad with her unwilling husband after difficulty conceiving
Elizabeth Banks as Wendy Cooper, Gary's wife and Theo's mother who becomes pregnant after trying for 2 years. Runs the Breast Choice Boutique.
Chace Crawford as Marco, who reunites with an old flame (Rosie) after a turf war between their respective food trucks
Brooklyn Decker as Skyler Cooper, the wife of a much older man named Ramsey, stepmother of Gary who becomes pregnant with twins Aida & Nida
Ben Falcone as Gary Cooper, Wendy's husband, Theo's father, Ramsey's son, Skyler's stepson, and Aida & Nida's older paternal half-brother
Anna Kendrick as Rosie Brennan, who reunites with an old flame (Marco) and fellow food-truck owner and becomes pregnant unexpectedly and has a miscarriage
Matthew Morrison as Evan Webber, who teams with Jules on a celebrity dance show and the father of her baby girl named Emerson
Dennis Quaid as Ramsey Cooper, Skyler's husband, Gary, Aida & Nida's father and Theo's paternal grandfather
Chris Rock as Vic Mac, founder of the "dude group" and father of four.
Rodrigo Santoro as Alex Castillo, Holly's husband who's in the music business and is not ready to have an adopted son named Kaleb
Joe Manganiello as Davis
Rob Huebel as Gabe, a new parent who adjusts to "fatherdom" by bonding with other dads in a city park-based group that is part playgroup, part secret society for dads only
Thomas Lennon as Craig, a father who joins Vic's "dude group"
Amir Talai as Patel, a father who joins Vic's "dude group"
Rebel Wilson as Janice, an eccentric employee at The Breast Choice boutique
Wendi McLendon-Covey as Kara, Holly's co-worker and friend
Dwyane Wade has a cameo as himself
Whitney Port has a cameo as herself
Megan Mullally has a cameo as herself
Taboo has a cameo as himself
Whitney Bischoff has a cameo as herself
Katherine Heigl has a cameo as herself
Serena Williams has a cameo as herself
Kim Fields as Renee Thompson, social worker who helps out a couple with an adoption
Jesse Burch as Hutch Davidson
Josh Segarra as Brett, Rosie's nerd roommate
Mimi Gianopulos as Molly, Rosie's funny roommate who comforts and supports her
Genesis Rodriguez as Courtney, Rosie's roommate
Sean Holland as Joey, Rosie's social worker
Hannah Kahlsulka as Grenda, Skyler's goofy friend at restaurant
Louisa Lytton as Meredith, Skyler's goofy friend
Roxane Hayward as Mickie, Skyler's goofy friend at restaurant
Odette Yustman as Bella, Skyler's goofy friend at restaurant
Dominique McElligott as Sterling, Skyler's goofy friend at restaurant
Joanie Sprague plays a clown at a restaurant
Olivia Scriven, Julia Barnett Tracy, Devin Kelley, Emmanuelle Chirqui, and Karrie Otis play restaurant chefs