—For God's sake, Sheldon, do I have to hold up a sarcasm sign every time I open my mouth? —You have a sarcasm sign?

Which duo on The Big Bang Theory has the best chemistry? The relationship could be friendly, romantic or snarky, but it’s entertaining and you enjoy watching the pair interact on screen and look forward to more scenes with them. Vote away!

An infographic illustrating Sheldon's t-shirt collection and wearing habits.

Cool sheldon sarcasm shirt

The Big Bang Theory: The Party Game Breaking News

Large print Sheldon shouting his arch nemesis' name