Poppy, a friend of mine on the vampire-diaries.net forums, recently traded a few e-mails with LJS and asked about Damon/Meredith as a possibility and LJS gave a little bit about her plans for Meredith's future storylines (even is they won't be used by the ghostwriter).
Pith/Poppy: I could have sworn you had a part in a blog or something where you said you saw potential for Damon & Meredith. Now, Damon/Elena and Damon/Bonnie fans are swearing up and down that this is impossible, but I don't think so. But Chapter 8 in Midnight, at least to me, shows that Damon *respects* Meredith, and that's...
A lot of us have to wait till mid March or longer for Midnight to come out. But I've seen tweets from people in Australia(where it was released today) who have the book about events and quotes regarding DE.
WARNING: VERY SPOILERY
-Damon to Elena: "Will you remember? Just that...I loved once, just once, really, in my whole life. Can you remember that I loved you?"
-"There was no world for her if there was no Damon"
-Stefan apologizes for coming in between them, he didn't understand how much they loved each other.
-In the motel she held him all night because he didn't want to feel alone