When the theme and setting of a popular television show is based on a U.S. city, it can do wonders for travel the destination: whether it's high-heeled ladies seeking the "Sex and the City" experience in New York or the hard-working (or hardly-working) employees visiting Scranton, PA for a day at "The Office."

Although Philadelphia needs no introduction, the City of Brotherly Love could benefit from the increasing popularity of FX's "It's Always Sunny in Philadelphia," starring Danny Devito. The show recently got picked up by Comedy Central for syndication and is now getting an official tour itinerary.

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