#1: BILLY GREY:
Not only throws you under the bus, but he'll take a shit on you afterwards..


#2: PATRICK STAR:
"He's been doing it on purpose. He's always been doing it on purpose. Everything you have seen on this list has been completely intentional. He knows he's stupid, or at least he's pretending to be stupid. Unlike Breath of Fresh Squidward, this also affects appearances shown afterwards, even more so than the ones shown before. I stand strong in my statement that this is more of a monster than Puffy Fluffy ever was. He has become a fucking sociopath, blind to the fact that his actions can and do harm to those around him. Those he used to pretend to care about, those he shared fake laughter with, Those he pretended to cry for, To think that my dog was named after this GROTESQUE CANCER OF IMAGINATION!"
~ TheMysteriousMrEnter


#3: ERIC CARTMAN:
Despite being one of the five main characters on the show, and arguably the most popular and mascot, Cartman is evil, sociopathic, foul-mouthed (the most foul-mouthed on the show), lazy, selfish, spoiled, greedy, and openly prejudiced against anyone who is not a heterosexual Caucasian male. Cartman usually does and says despicable things for fun or a higher self-serving purpose, such as theft, lying, slander, even tourture and murder. He once calmly said that other peoples pain and suffering amuses him, seemingly not realizing that this was a bad thing. On occasions he embraces the negative side of life, such as willingly and knowingly being a fearmonger for petty, selfish reasons. He is constantly making nasty remarks at the expense of Hebrews, African Americans and flatly thinks females are automatically inferior to males in everything. He also stereotypes every race and religion (positively and negatively) without hesitation or shame. Due to the messed up nature of South Park, his stereotyping usually turns out right..


#4: TREVOR PHILLIPS:
Best to just avoid him..


#5: HAROLD "STRETCH" JOSEPH:
Throws you under the bus just "cause"..


#6: PETER GRIFFIN:
He probably means well, but he is not as nice a character as some may imagine - in fact throughout the course of the series, Peter has caused much misery for those around himself: often this is due to stupidity but there have been times when Peter has deliberately caused harm or misfortune on others to better himself, which only backfires, leaving Peter the raw end of the deal..


#7: JOE SWANSON:
Imagine someone screaming in your ear every five seconds..


#8: ROGER:
Roger is also shown to be a dangerous sociopath committing theft, various drug offenses and many counts of murder throughout the series. In "Virtual In-Stanity", he kills five people plus a planeload of innocent victims for twenty dollars and mentions killing six others for nineteen dollars. In "Toy Whorey", he allowed Francine to be struck by a wrecking ball in order to have her steak as well as his own, and when asked by Klaus if Francine was dead, he showed no concern of any kind..


#9: ROY EARLE:
Earle, like Phelps, is no stranger to fist-fights and shootouts. In addition, Earle occasionally shows little regard for Phelps' safety, as well as his OWN safety.
During shootouts, Roy is a lot more careless than Cole's other partners. He rarely uses cover and usually can be seen to fire his weapon from the hip one-handed. Despite this, he still mocks Cole for not taking cover.

Earle is also an opportunist. He stole a roll of money worth $1,000 which was actually evidence, after claiming "the department owed him fifty," when the department only owed him $20. He also evidently took bribes and had a personal stake in the fixed boxing match between Albert Hammond and Kid Galahad. He also tells Phelps in The Black Caesar that he wanted to wrap up the case before he had to actually work overtime instead of just claiming it and therefore receive extra pay. Furthermore, Earle knew of Phelps' interest in Elsa, and ultimately used this information to bargain his way into the SRF syndicate and into Leland Monroe's payroll..


#10: MOE:
Anytime one of your supposed "best friends" tries to cozy up to your wife, you have to seriously reconsider why the hell you're friends with that person in the first place. In Moe's case, he tried repeatedly to pry "Midge" away from Homer Simpson. Heck, even in the last Treehouse of Horrors special, Moe actually wrote a musical that was all about accidentally killing Homer and trying to steal Marge. On top of that, when Homer invented a great new drink, Moe stole the recipe, dubbed it the "Flaming Moe," made a fortune, and didn't give his buddy any of the credit. Yet after all these years Homer still calls Moe a friend. It probably helps his cause that he's the guy who gets Homer loaded so often.